Growth Hormone Deficiency
Adult growth hormone deficiency (AGHD) is an under-recognized condition that contributes to abnormal body composition, reduced quality of life, dyslipidemia, and reduced bone density. It is most commonly caused by pituitary tumors or their treatment. GH replacement in confirmed deficiency improves body composition, bone density, lipids, and subjective wellbeing.
When to Book
Book a visit if symptoms are new, persistent, getting worse, or affecting daily life. Early evaluation often prevents complications.
Symptoms
Increased body fat (particularly visceral), decreased lean muscle mass, fatigue, reduced exercise capacity, poor quality of life, low mood, impaired memory and concentration, reduced bone density, and an adverse lipid profile.
Causes & Risk Factors
Pituitary adenoma or its treatment (surgery, radiation) is the most common cause in adults. Traumatic brain injury, cranial radiation for other tumors, and childhood GH deficiency that persists into adulthood are other causes. Severe AGHD is defined biochemically by a GH stimulation test.
How We Evaluate
IGF-1 is a screening test — a low value in the appropriate clinical context is strongly suggestive. Dynamic stimulation testing (insulin tolerance test or glucagon stimulation test) is the gold standard for diagnosis. Full pituitary hormone panel, bone density (DEXA), and fasting lipid panel complete the evaluation.
Treatment Options
Recombinant human growth hormone administered by daily subcutaneous injection. Doses are titrated to maintain IGF-1 in the mid-normal range. We monitor for side effects including fluid retention, arthralgia, and glucose intolerance. Response is assessed by body composition, bone density, and quality-of-life measures.
When It Is Urgent
Growth hormone deficiency is not an emergency. In a patient with a known pituitary tumor, sudden neurological symptoms require urgent evaluation for apoplexy or expansion.
Frequently Asked Questions
Do I need a referral to see an endocrinology provider?
No referral is needed at Nomi Beach Health. You can book directly with our team for hormone, thyroid, metabolic, or weight-management concerns.
How long does it take to see results from treatment?
Timeline depends on the condition. Thyroid medication often improves symptoms within four to eight weeks. Weight-loss interventions show measurable changes in four to twelve weeks. Hormone therapy timelines vary by the specific condition and individual response.
Will I need labs before my first visit?
You can come in without prior labs — we order whatever is appropriate during or after your visit. If you have recent results, bring them so we can start the conversation right away.
Are these conditions managed long-term or treated once?
Most endocrine and metabolic conditions require ongoing management rather than a single treatment. We build a follow-up schedule around your specific diagnosis and goals.
Can I be seen for weight loss even if I do not have a hormone diagnosis?
Yes. We evaluate weight holistically — including metabolic markers, lifestyle factors, and, when appropriate, medication options such as GLP-1 agonists.
Get a Clear Plan for Growth Hormone Deficiency
Our endocrinology team evaluates you as an individual and builds a treatment plan that fits your life — not a template.